Lacy, MD, PhD, in their book Healing Heartburn. There are dozens of NSAIDs, including over-the-counter aspirin, Best cure for bad heartburn Motrin, Advil, Nuprin , and naproxen Aleve , as well as prescription anti-inflammatory medicines. Normally, the LES closes as soon as food passes through it. Heartburn can also be a symptom of a medical condition, most commonly of gastroesophageal reflux disease or GERD acid reflux . What next? Endoscopic injection of bulking agents involves a surgeon injecting a filler where the stomach and oesophagus meet, narrowing the junction and helping to stop acid leaking up from the stomach. In this eBook, youll learn how to optimize your gut health—and by extension, your overall health—with simple diet and lifestyle changes. You may also want to keep a food diary to help identify problem foods. which run through the gastrointestinal tract.