This may happen if you have: Step-down . Both classes of drugs are effective in relieving GERD, but they have different timing. Long-term use of PPIs may reduce the duration of treatments. Chewing gum stimulates the salivary flow rate, and any acid that accumulates in your stomach is washed away and cleared more quickly. Oh yeah, Gerd treatment and drugs have to sleep sitting up,' Verdin said happily. Many gastrointestinal diseases such as inflammatory bowel disease, ulcers, and intestinal cancers can cause symptoms similar to GERD, but they can be diagnosed correctly because they produce additional symptoms and affect different areas of the intestinal tract. Try an acid suppresser. Some experts recommended that patients who are on PPIs take an H2 blocker only to prevent breakthrough symptoms, such as before a heavy meal.