People who are overweight or older tend to be affected more since abdominal fat interferes with Heartburn remedy for pregnancy function, and the esophageal sphincter, which prevents backsplash, weakens with age. H2 blockers, such as Zantac, Pepcid and Axid, are successful at treating heartburn and reflux, but they are less effective at treating inflammation in the esophagus that can be caused by GERD. By design the sphincter should keep a tight seal, only allowing food and drink to travel in a downwards direction, not the reverse. Take 2 to 3 capsules of digestive enzymes with each meal. Food and Drug Administration Consumer Health Information. The National Institute for Health and Care Excellence NICE has looked at many of these new techniques and states that they are safe enough to be made Heartburn remedy for pregnancy on the NHS. Cheskin, MD, and Brian E. Among the 322 people using PPIs in the ARIC study, the 10-year estimated absolute risk for chronic kidney disease was 8 percent, the researchers reported.