We have all faced the symptoms acid reflux disease, known as heartburn after a particularly spicy meal. Many different medicines can trigger heartburn or make heartburn worse. If the pressure barrier is not enough to prevent regurgitation and acid backs up reflux , peristaltic action of the esophagus serves as an additional defense mechanism, pushing the backed-up contents back down into the stomach. GERD is first treated with over-the-counter methods, such as antacids and dietary changes. so I usually take a Zantac 75 right before bed, and it Home remedies for extreme acid reflux a lot. Tobacco inhibits saliva, which is the body's major buffer. Normally, your esophagus is protected from this acid in your stomach by a muscle called the lower esophageal sphincter. Feeling hopeless about acid reflux. A foam block placed under the head of the mattress works well, as does a wedge pillow.