Giving up smoking can help, as smoke irritates your digestive system and can make your symptoms worse. In prescription form usually higher doses , Zantac, Tagamet, Pepcid, and Axid can generally relieve heartburn and treat gastroesophageal reflux disease GERD . This can be harmless and perfectly natural in infants under 18 months old. If the baking soda treatment is used regularly, then it will increase the sodium content in your body, which can lead to a host of other ailments, such as swelling in your joints or nausea. You may experience indigestion at any point during your pregnancy, although your symptoms may be more frequent and severe during later pregnancy, from 27 weeks Zantac for heartburn relief 3 Do not drink fluids around meal time. Many people have reflux regularly and it's not usually a cause for concern. Proton pump inhibitors.